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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Karnesafta (erennette) is a combination of two nutrients: tryptophan and niacin. Karnesafta is an herbal supplement that stimulates the growth and release of niacin from bacteria.
  • Alkemptical (exercise-trained) capsules: capsule shellac acid alkemptical (exercise-trained inhalation technique) improves blood flow to the penis, leading to reduced pain and swelling in sensitive individuals.
  • C.

    The following key drug-food interactions are not managed by Cialis: Telithromycin, itraconazole (used to manage bacterial infection), nitroprusside, rifampicin, or if you use nitrate medications for angina.

    D.

    Similar to serotecan, these two medications can interact with certain foods and beverages, such as grapefruit and grapefruit juice, increasing the risk of side effects. Avoid consuming grapefruit or grapefruit juice while using Cialis.

    Interactions

    A. Top Drug-Drug Interactions:

    1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

    2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

    3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

    Other Drug-Drug interactions:

    • Ketoconazole, itraconazole (used to manage fungal infection)
    • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
    • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
    • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
    • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

    B. Drug-Food Interactions:

    Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

    1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
    2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
    3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
    4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
    EU Antibiotic look like a mouthful; what do you need?

    When taking Cialis and its effects, it is important for your doctor to determine the appropriate dosage and monitor you regularly for side effects. Below are some common dosage forms of these antibiotics:

    • Anastrozole, irbyaconazole, or ketoconazole (Z-Y bleeding)
    • Oral vancomycin
    • vaginal thrush

    It is important to note that Cialis should not be taken more than once in a 24-hour period, and your doctor will need to adjust the dosage as needed to maintain effective blood pressure management.

    C. Other Anti-hypertensive Drugs (Phosphodiesterase-5 Inhibitors):

    Ex. I.p. atropine, alogliostasis (used to manage hypertension), angina, a heart attack, or a stroke, cilostazol (used to manage angina) or phentermine HCl

    D.

    Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

    Common side effects reported from Cialis use include:

    • Headache
    • Indigestion
    • Heartburn
    • Upset stomach
    • Gas
    • Nausea
    • Flushing

    More severe side effects include:

    • Painful erections or erections that last longer than 4 hours
    • Sudden loss of vision
    • Sudden loss of hearing
    • Ringing in the ears
    • Chest pain
    • Shortness of breath
    • Painful urination
    • Increased urination frequency
    • Fainting
    • Dizziness
    • Skin rash
    • Hives
    • Facial swelling

    If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

    As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

    Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

    In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

    Show More Nov 28, 2023ometown, Ohio, United States -- Cialis is a popular prescription medication used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) in men. Viagra is a sexual-stimulating drug (SSRI) used to treat erectile dysfunction and pulmonary arterial hypertension. Cialis does not work if you have an erection that lasts more than 4 hours.Show More Nov 28, 2023ometown, Ohio, United States - Cialis is a prescription medication used to treat erectile dysfunction and pulmonary arterial hypertension. It does not increase sexual desire or treat erectile dysfunction. Viagra is a prescription-only medication used to treat erectile dysfunction. Cialis can also be purchased over the counter (without a prescription) in some countries.

    If you take Cialis with food or milk and you are not enjoying the medication, please do not take it without consulting your doctor. Cialis can affect your libido and could increase the risk of getting caught. Sexual stimulation is not recommended because Cialis can cause an erection that lasts longer than 4 hours.

    This medication can also affect the way other medicines work, increasing side effects or reducing the effectiveness of Cialis.

    If you are taking nitrates or other medications to treat high blood pressure, Cialis can lower blood pressure. Combining Cialis with these medications can cause a dangerous drop in blood pressure.

    Do not take Cialis if you are allergic to any of the ingredients in Cialis. Before taking Cialis, tell your doctor if you have any of the following:

    • Alpha-blockers
    • Amlodipine
    • Amphetamine salts
    • Diphenhydramine
    • Guanfacine

    Information on using Cialis without a doctor's permission is available in the Cialis FAQ section.

    Cialis can cause side effects, including:

    • Facial flushing
    • Muscle aches
    • Back pain
    • Mild headacheLAND

    This is not a complete list of Cialis side effects. If these are not mild, your doctor may advise against using Cialis.

    If you experience any serious side effects, please seek medical attention immediately.

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